Disease: Parkinsonism, Juvenile
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC30A10 Q6XR72 solute carrier family 30 member 10 Transporter 0.98 0.578 0.654
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769
RAB39B Q96DA2 RAB39B, member RAS oncogene family 0.83 0.619 0.615
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
PRKRA O75569 protein activator of interferon induced protein kinase EIF2AK2 Kinase 0.42 0.579 0.615
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PNOC Q13519 prepronociceptin Signaling 1.5E-02 0.603 0.577
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808
NIF3L1 Q9GZT8 NGG1 interacting factor 3 like 1 9.7E-09 0.674 0.462
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885